Clinical case 3

A 35 year old male executive in a multinational company complains of dull pain in the midepigastric region for the last one month. The pain gets worse at night and is somewhat better immediately after he eats his meals. There is no history of any fever, nausea or vomiting. He has been frequently taking analgesic ( about 1-2 tablets per week) for headache but there is no history of intake of any other medications.

He underwent upper GI endoscopy once earlier, but no records are available with him.

What is the probable diagnosis?

Discuss the clinical correlation with pathogenesis of the features.

How will you investigate and confirm the diagnosis?

Clinical case 2

A 75 year old man, living on his own, brought by the neighbour to the Emergency Department of the hospital with fever, fatigue, malaise and a productive cough since 15 days. He also gives history of chills and rigors. On examination, he has crepts and rhonchi in both the lungs

What is the probable diagnosis

Discuss the clinical correlation with pathogenesis of the features

How will you investigate and confirm the diagnosis

Clinical case 1

A 54 year old male complains of persistent productive cough for 2 years. Lately, for the last 2 months, there is intermittent blood in the sputum. There is history of progressive loss of weight and appetite for 1 month and occasional chest pain. He has been a chronic smoker, smoking about 20 cigarettes/ day for the last 30 years and is an occasional alcoholic.

On examination, pallor ++, icterus -ve, clubbing of fingers – grade II. On inspection of chest, left half of chest is not moving equally with respiration. On auscultation, breath sounds absent on left side

What is the probable diagnosis

Discuss the clinical correlation with pathogenesis of the features

How will you investigate and confirm the diagnosis