A 35 year old male executive in a multinational company complains of dull pain in the midepigastric region for the last one month. The pain gets worse at night and is somewhat better immediately after he eats his meals. There is no history of any fever, nausea or vomiting. He has been frequently taking analgesic ( about 1-2 tablets per week) for headache but there is no history of intake of any other medications.
He underwent upper GI endoscopy once earlier, but no records are available with him.
What is the probable diagnosis?
Discuss the clinical correlation with pathogenesis of the features.
How will you investigate and confirm the diagnosis?
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