Clinical case 1

A 54 year old male complains of persistent productive cough for 2 years. Lately, for the last 2 months, there is intermittent blood in the sputum. There is history of progressive loss of weight and appetite for 1 month and occasional chest pain. He has been a chronic smoker, smoking about 20 cigarettes/ day for the last 30 years and is an occasional alcoholic.

On examination, pallor ++, icterus -ve, clubbing of fingers – grade II. On inspection of chest, left half of chest is not moving equally with respiration. On auscultation, breath sounds absent on left side

What is the probable diagnosis

Discuss the clinical correlation with pathogenesis of the features

How will you investigate and confirm the diagnosis

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